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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '379c17096c982c94398cd0b9c7351e32a0f0e8f543640559e309fa4d4ece4250' 
  AND token = 'aIa/dt2g8G/DVyNDtv42LuDQ9alliP2Clwdy008icSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}