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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '2149c907aebdc41916dadd66e8a821bb14f850b5a5fc70dd1037f184d2a691bb' 
  AND token = 'IHuyJ+hY9CHvxqyoZJCvpRQBE7lixv80Wg/oEHtyNcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}