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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = 'ac05a1edf77770d976256e6e0c464467a86ece4317799cefb844091253ee0a49' 
  AND token = 'yfPYdFWXaFTFhr/AcRMCobUnrbeHS29U8+2+Pe19erQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}