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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '0bc36b7d820fbe86f5668bf408542eadbda7656627d378088d550216e93af758' 
  AND token = 'guhDUwP0AcTYmdihBPPd8EI4tdK5dHzhgjVnEUZ36cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}