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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '50f81b467a16fc2bd7e721ea9dd874cd469bfdb0611da4ecf8ff008c88a27153' 
  AND token = 'N4Y8YLEL+vJggTbbP3Xvo82eQiwQc3krzIqbG8JHWfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}