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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '49ec0b2ff5a06453db0f6a044153c929ad607f0290f3a543578bb98e8c7bb405' 
  AND token = 'yAx1uBX+y72tzCxDrLpk+NVX3tbd8h/jqu53c0ljwrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}