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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '64e359f2727bcbd86c488be604095aa70a7a21d56b14ad033233819c9c7c5a4f' 
  AND token = 'OH1sXXmOmXUiHy8PJtMkh0cTym2Sff48RIaQOeFTl1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}