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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '6798f8d11b2028a936014066eb402eacadd173f345ceceb651d57b608cbf3d1d' 
  AND token = 'giIJorg4GYA2/FKwxN0MfL8UbD6+dMYJE/fOxHRA57o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}