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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '4e6d1cee2be3be6557c88172748d6fc2653fc70b0a500eaacb5dbefdc37203f9' 
  AND token = '1pFlzfsafpdBA00cTiKUY2/MiGERUlu835DKmWTkspY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}