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SELECT 
  1 
FROM 
  q_lock_keys 
WHERE 
  key_id = '15c41761f44641502599dfe7d1e842919ace4a0f051fdcccf83578f4f9216730' 
  AND token = 'uEREK/C3fujLFWYPPCskMWtm/KvikQ2934Xfeku7qJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}